Migumisiro Yemishonga Inodzivirira Kuzvimba
Mishonga inorwisa kuzvimba isiri yesteroid (NSAIDs) imhando yemishonga inowanzoshandiswa kuderedza kuzvimba, kuderedza marwadzo, uye kuderedza fivha. Mimwe mienzaniso yakakurumbira yemishonga iyi inosanganisira ibuprofen, aspirin, uye naproxen. Kunyange zvazvo ichishanda zvakanyanya mukurapa zvirwere zvakasiyana-siyana, kushandiswa kweNSAID hakurevi kuti hakuna migumisiro yayo . Chinyorwa chino chichakurukura migumisiro yakasiyana-siyana inogona kukonzerwa nekushandiswa kweNSAIDs.
1. Migumisiro Yakashata Pamushonga Wekugaya
Imwe yemigumisiro inozivikanwa zvikuru yekushandisa NSAIDs matambudziko ekugaya chikafu. Izvi zvinosanganisira zvirwere zvakasiyana-siyana, kubva pazviratidzo zvidiki zvakaita sekurwadziwa mudumbu uye kuda kurutsa kusvika kumatambudziko akakomba akadai semaronda emudumbu uye kubuda ropa mudumbu.
– Gastritis: Mishonga yeNSAID inogona kukuvadza jira rekudzivirira remudumbu, zvichikonzera kutsamwa nekuzvimba kwejira remudumbu. Zviratidzo zvinogona kusanganisira kurwadziwa mudumbu, kuda kurutsa, uye kurutsa.
– Maronda Emudumbu: Kushandiswa kwenguva refu kana mishonga yeNSAIDs yakawanda kunogona kuwedzera njodzi yekuve nemaronda emudumbu. Aya maronda akavhurika mudumbu kana muura hudiki anogona kukonzera kurwadziwa kwakanyanya uye matambudziko akakomba akadai sekubuda ropa.
– Kubuda ropa mudumbu: Mishonga yeNSAID inogona kukonzera kukuvadzwa kwedumbu nemukati medumbu, izvo zvinogona kukonzera kubuda ropa. Iyi idambudziko rehutano rinoda kurapwa nekukasika.
2. Migumisiro Yakashata Pamuviri Wemwoyo
Kushandiswa kweNSAID kwakabatanawo nematambudziko emwoyo. Ongororo dzakawanda dzakaratidza kuti kushandiswa kwenguva refu kwemamwe marudzi eNSAID kunogona kuwedzera njodzi yekurwara nemoyo uye sitiroko.
– Hypertension: NSAIDs dzinogona kukonzera kuchengetwa kwe sodium nemvura mumuviri, izvo zvinogona kukonzera kuwedzera kweBP kana kuwedzera BP yagara iripo.
– Njodzi yeKurwara neMwoyo neSitiroko: Mamwe maNSAID, kunyanya COX-2 inhibitors senge celecoxib, akabatanidzwa nekuwedzera kwenjodzi yekurohwa nemoyo nesitiroko. Nokudaro, kushandiswa kwenguva refu kunofanira kukurukurwa nachiremba, kunyanya kune avo vane nhoroondo yezvirwere zvemwoyo.
3. Matambudziko nekushanda kweitsvo nekubvisa tsvina
Mishonga yeNSAID inogona kukanganisa mashandiro eitsvo, kunyanya kana ikashandiswa kwenguva yakareba kana pahuwandu hwakawanda.
– Kukuvara kweKidney (AKI): Kushandiswa kweNSAID kunogona kukonzera kudzikira kweropa kuenda kuitsvo, zvichikonzera kukuvara kweitsvo zvakanyanya. Zviratidzo zvinogona kusanganisira kudzikira kwemvura inobuda muweti, kuneta, uye kuvhiringidzika.
– Kuchengetedza Mvura: Nekuda kwekushandiswa kweNSAIDs pakushanda kweitsvo, muviri unogona kuchengetedza mvura yakawanda. Izvi zvinogona kukonzera kuzvimba (kuzvimba) uye zvirwere zvakanyanya zvakaita sekushaya simba kwemoyo.
4. Kurwara neAllergy uye Asthma
Kunyangwe zvisingawanzoitiki, vamwe vanhu vanogona kusangana neallergies dzakakomba kana vakashandisa NSAIDs. Uyezve, pane hukama huripo pakati pekushandiswa kweNSAIDs nekuwedzera kweasthma mune vamwe vanhu.
– Kurwara neAllergy: Zviratidzo zvekurwara neNSAID zvinogona kusanganisira mapundu, mapundu eganda, kuzvimba kwechiso kana rurimi, uye muzviitiko zvakanyanya, anaphylaxis, iyo inoda kurapwa nekukurumidza.
– Kuwedzerwa kweAsthma: Vamwe vanhu vane asthma vanogona kubatwa nechirwere cheasthma mushure mekutora NSAIDs. Ichi chiitiko chinozivikanwa se "aspirin-exacerbated respiratory disease" (AERD).
5. Migumisiro Yakashata PaSisitimu Yetsinga Yepakati
Vamwe vanoshandisa NSAID vanotaura nezvemigumisiro inokanganisa tsinga dzemutsinga, kunyange hazvo izvi zvisingawanzoitiki.
– Musoro neDzungu: Kushandiswa kweNSAIDs, kunyanya kwenguva refu kana kuti muhuwandu hwakawanda, kunogona kukonzera misoro nedzungu.
– Kuvhiringidzika uye Kuora Mwoyo: Migumisiro iyi haiwanzoitiki asi ichiripo, kunyanya kune vakwegura. Kuvhiringidzika, kurara zvakanyanya, uye kunyange kuora mwoyo zvakambotaurwa mune dzimwe nguva.
6. Kudyidzana Nemimwe Mishonga
Mishonga yeNSAID inogona kushanda pamwe chete nedzimwe mhando dzemishonga, izvo zvinogona kuchinja kushanda kwayo kana kuwedzera njodzi yemigumisiro yakaipa.
– Mishonga Inorwisa Kubuda Kweropa: Kushandisa NSAIDs pamwe chete nemishonga inorwisa kuungana kweropa (yakadai sewarfarin) kunogona kuwedzera njodzi yekubuda ropa.
– Mishonga yekuderedza BP: Mamwe maNSAID anogona kuderedza kushanda kwemishonga yekuderedza BP, zvichiita kuti kudzora BP kuve kwakaoma.
– Lithium: Mishonga yeNSAID inogona kuwedzera huwandu hwe lithium muropa, iyo inoshandiswa kurapa chirwere chepfungwa chinoputika, nokudaro ichiwedzera njodzi yekukuvadzwa ne lithium.
Mhedziso
NSAIDs mishonga inoshandiswa zvakanyanya nekuda kwekushanda kwayo mukurapa kuzvimba, marwadzo, uye fivha. Zvisinei, semishonga yese, kushandiswa kweNSAID kune njodzi. Migumisiro inowanzo sanganisira kugaya, hurongwa hwemwoyo, itsvo, allergic reactions, uye kunyange hurongwa hwetsinga. Uyezve, kusangana nemimwe mishonga kunogonawo kuwedzera njodzi yemigumisiro.
Mishonga yeNSAID inofanira kushandiswa nguva dzose zvichienderana nemirairo yachiremba kana mirairo iri papakeji. Zvakakosha kunzwisisa njodzi dzinobatanidzwa uye kutsvaga rubatsiro rwechiremba nekukurumidza kana paine zviratidzo zvisingawanzoitika kana kusawirirana kwakaitika . Kune vanhu vane mamwe mamiriro ehutano, akadai sechirwere chemwoyo, BP, chirwere cheitsvo, kana asthma, kubvunza chiremba usati washandisa mishonga yeNSAID kwakakosha kuderedza njodzi yemigumisiro yakakomba.
Nekunzwisisa kwakanaka kwemigumisiro inogona kuitika, vatengi vanogona kuita sarudzo dzakangwara maererano nekushandiswa kweNSAID uye kuchengetedza hutano hwavo zviri nani.
