Zviratidzo zveKliniki uye Kurapwa kweFIP mumakati
Chirwere cheFeline Infectious Peritonitis (FIP) ndechimwe chezvirwere zvinotyiwa zvikuru pakati pevaridzi vekatsi nekuti chinogona kukura nekukurumidza uye, kare, chaiwanzoonekwa se "mutongo" waive wakaoma kurapa. FIP inoitika nekuda kwehutachiona hweFeline Coronavirus (FCoV), iyo inochinja mumuviri wekatsi, yozokonzera kuzvimba kwakasimba mutsinga dzeropa (vasculitis) nedzimwe nhengo dzakasiyana-siyana. Zvakakosha kunzwisisa kuti havasi vese FCoV vanozokura kuita FIP; katsi zhinji dzinosangana neFCoV dzinosangana nematambudziko mashoma ekugaya kana kuti dzisina zviratidzo. Zvisinei, mune dzimwe nguva, hutachiona hunochinja uye hunokura kuita FIP.
Chinyorwa chino chinokurukura zviratidzo zveFIP mumakati uye nzira dzekurapa nadzo, kusanganisira rubatsiro rwekutsigira uye mushonga wekudzivirira utachiona uri kushandiswa pari zvino.
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Kunzwisisa FIP: Sei Ichiitika?
FCoV inowanzo pararira kuburikidza netsvina, kunyanya munzvimbo dzine katsi dzakawanda (dzimba dzine katsi dzakawanda, nzvimbo dzekuchengetera mhuka, kana nzvimbo dzezvipfuyo). Utachiona uhwu hunopinda mudumbu uye kazhinji hahukuvadzi. Matambudziko anomuka kana hutachiona hukachinja mumuviri wekatsi, zvichiita kuti irarame mumasero ekudzivirira muviri (macrophages) uye ipararire mumuviri wese. Kudzivirira kwekatsi kunobva kwakonzera kuzvimba kwemuviri kunokuvadza mitsipa yeropa nematishu.
Zvimwe zvinhu zvinofungidzirwa kuti zvinowedzera njodzi yeFIP zvinosanganisira:
– Katsi dziri zera rechidiki (kazhinji < makore maviri) kana kuti dzakura zvakanyanya, - Kushushikana (nzvimbo yekutama, kuvhiyiwa, pamuviri, nzvimbo yakazara vanhu), - Kusadzivirira muviri zvakanyanya kana zvimwe zvirwere, - Zvikonzero zvemajini mune mamwe marudzi. --- Marudzi eFIP: Akanyorova (Anobuda) uye Akaoma (Asingabude) Mukurapa, FIP inowanzo kamurwa kuita marudzi maviri makuru, kunyangwe muchokwadi katsi zhinji dzichiratidza musanganiswa wezvose zviri zviviri. 1) Akanyorova (Anobuda) FIP Iyi fomu inoratidzwa nekuungana kwemvura mumipata: - Dumbu (ascites) → dumbu rakakura, rinonzwa "rakazara nemvura" - Chifuva (pleural effusion) → kufema kushoma, kufema nekukurumidza, kushaya simba. Mamiriro acho anogona kuipa munguva pfupi. Katsi inoita seisina simba, ine chido chekudya chakaderera, uye inorasikirwa nehuremu nekukurumidza.
2) Dry FIP (Isina kuyerera) Muchimiro ichi, mvura hainyanyi kuwanda, asi kuzvimba kwegranulomatous kunoitika munhengo dzakadai se: - chiropa, - itsvo, - spleen, - ura, - lymph nodes, - maziso, uye tsinga.
Zviratidzo zvinowanzova zvishoma uye zvinogara kwenguva yakareba kupfuura FIP yakanyorova, zvichiita kuti zviome kuona nekukurumidza.
--- Zviratidzo zveFIP mumakati Zviratidzo zveFIP zvinosiyana zvikuru, zvichienderana nenhengo dzakabatwa uye chimiro chechirwere. Heano zviratidzo zvinowanzoonekwa: Zviratidzo Zvose - Fivha inokwira nekudzika uye kazhinji isingapindure nemishonga inorwisa mabhakitiriya - Kuneta, kurara nguva dzose, kusaita maekisesaizi - Kudzikira kwechido - Kudzikira kwehuremu - Kusanzwa kusimba, kushaya mvura mumuviri - Ma lymph nodes akakura mune dzimwe nguva Zviratidzo zveWet FIP (mvura mudumbu/pachipfuva) - Dumbu rakakura risina kuwedzera chido (ascites) - Kufema zvishoma, kufema nekukurumidza, kugara pasi nemutsipa wakatambanudzwa (kana mvura iri muchipfuva) - Kufema kusina simba kana uchiongororwa nachiremba wemhuka - Dzimwe nguva kuperekedzwa nekurutsa kana manyoka madiki Zviratidzo zveDry FIP (yakanangana nenhengo) Nekuti inosanganisira nhengo, zviratidzo zvinogona kusiyana: - Itsvo: kunwa doro kakawanda, kuita weti kakawanda, kudzikira kwemuviri, zviratidzo zvezvirwere zveitsvo - Chiropa: yero (jaundice), kurutsa, kudzikira kwechido, kusagadzikana mudumbu - Matumbu: manyoka asingaperi, kudzikira kwehuremu, dumbu rinonzwa - Ma lymph nodes emudumbu akakura: dumbu rinoita se "rakazara" asi harisi nguva dzose rine mvura Ocular FIP (maziso) FIP inogona kukonzera kuzvimba kwemaziso, semuenzaniso: - uveitis (maziso matsvuku, anorwadza), - kusaenzana kwevadzidzi, - kuchinja kweruvara rwemukati meziso, - kusaona zvakanaka.
Zviratidzo zvemaziso dzimwe nguva chiratidzo chakakosha cheFIP yakaoma.
FIP yetsinga Iyi ndiyo mhando yakanyanya kuomarara. Zviratidzo zvacho ndeizvi: - kuzununguka (ataxia), - pfari, - kudedera, - kuchinja maitiro, - kurereka musoro, - kushaya simba mumakumbo.
--- FIP inoonekwa sei?
Kuongororwa kweFIP hakusi nyore nguva dzose nekuti hapana bvunzo imwe chete "yakapfava" inosimbisa pakarepo nyaya dzese. Chiremba wemhuka anowanzo sanganisa zvinotevera: - Nhoroondo uye kuongororwa kwemuviri (fivha, kudzikira kwehuremu, mvura iri mudumbu), - Kuongororwa kweropa: anemia, kuwedzera kweglobulin, low albumin/globulin (A/G) ratio, kuzvimba, - Ultrasound kana x-ray kuti uone shanduko dzemvura kana nhengo, - Kuongorora mvura (muFIP yakanyorova): mvura yacho inowanzova yakakora, yero, ine mapuroteni akawanda, - Kuongororwa kwePCR/viral, kunyanya pane mamwe masampuli emvura/nyama, - Kuongororwa kwenyama (biopsy) uye immunohistochemistry, iyo iri pedyo nechokwadi mune dzimwe nguva.
Zvakakosha: bvunzo dze coronavirus antibody dzinongoratidza chete kusangana neFCoV, kwete kusimbisa FIP, sezvo katsi dzakawanda dzine hutano dzinewo antibody positive. --- Kurapa FIP muKatsi 1) Kurapa kweAntiviral (kurapa kukuru kunofadza) Mumakore achangopfuura, kurapwa kwe nucleoside analog-based antiviral therapy senge GS-441524 (uye mune mamwe ma protocol, remdesivir semushonga unoshanda) kwave kucherechedzwa nekuda kwekubudirira kwayo kwakanyanya muzviitiko zvakawanda, kusanganisira zvimwe zvine chekuita nemaziso netsinga (kunyangwe kazhinji zvichida madosi akanyanya uye nguva yakareba). Nheyo dzekurapa: - inopiwa zuva nezuva kwenguva yakatarwa (kazhinji mavhiki angangoita gumi nemaviri mu ma protocol akawanda ekiriniki), - dosi inogadziriswa zvichienderana nehuremu hwemuviri uye chimiro cheFIP (yakanyorova/yakaoma/yemaziso/yetsinga), - kuongororwa nguva dzose: huremu hwemuviri, kuda kudya, tembiricha, kuongororwa kweropa, uye kutarisa zviratidzo. Nekuti kuwanikwa kwemishonga nemitemo zvinogona kusiyana nenyika/dunhu, zvakakosha kubvunza zvakananga chiremba wemhuka ane ruzivo nezvekuvandudzwa kwazvino uye ane ruzivo mukurapa FIP. 2) Kutarisira Kunotsigira Kunyangwe mishonga yekudzivirira utachiona ichibatsira zvikuru, kuchengetedza kunotsigira kunoramba kwakakosha, kunyanya kana katsi isina simba: - Kurapa kwemvura inoyerera mvura mumuviri uye kuchengetedza kushanda kwenhengo - Kudya kunovaka muviri kwakawanda nemapuroteni (chikafu chinopora, rubatsiro rwekudya kana zvichidikanwa) - Mishonga yekudzivirira kuda kurutsa uye mishonga yekudzivirira dumbu kana kurutsa - Zvinodzivirira dumbu kana rutsigiro rweitsvo zvichienderana nenhengo dzakabatwa - Okisijeni kana paine kupererwa kwemweya nekuda kwemvura muchipfuva - Kubuda kwemvura (abdominocentesis/thoracocentesis) muFIP yakanyorova kubatsira kufema nekunyaradza, zvinoitwa nachiremba wemhuka nekuti pane njodzi yekudzoka kwemvura neprotein kusawirirana. 3) Kushandiswa kweAnti-inflammatory uye Immunomodulators Munguva isati yatanga hutachiona, corticosteroids yaiwanzopihwa kudzvinyirira kuzvimba, asi mhedzisiro yacho yaingova yenguva pfupi uye haina kugadzirisa chikonzero chacho. Parizvino, kushandiswa kwesteroids kunofanirwa kufungwa nokungwarira uye chete pasi pekutungamirirwa nachiremba wemhuka, kunyanya kana katsi iri kurapwa nehutachiona (nekuti kudzvinyirira immune system kunogona kukanganisa hutachiona hwechipiri).
Mishonga inorwisa mabhakitiriya haiwanzo batsira FIP zvakananga kunze kwekunge hutachiona hwechipiri hwaonekwa. --- Kufanotaura uye Mikana Yekupora Kufanotaura kweFIP kunoenderana zvakanyanya ne: - kuti inoonekwa nekukurumidza sei uye kurapwa kunotanga, - chimiro chechirwere (chakanyorova, chakaoma, chetsinga, chemaziso), - mamiriro enhengo panguva yekutanga kurapwa, - kutevedzera nguva uye chiyero chekurapa, - mhando yekutarisa uye rutsigiro rwekudya. Nenzira dzemazuva ano dzakavakirwa pamishonga inorwisa mabhakitiriya uye kutarisa kwakanaka, mikana yekuregererwa muzviitiko zvakawanda yakashumwa kuti yavandudzwa zvakanyanya zvichienzaniswa nekare. Zvisinei, katsi yega yega yakasiyana, uye nyaya dzakaoma dzichiripo, kunyanya kana paine kukuvara kwakanyanya kwenhengo kana kubatanidzwa kwakanyanya kwetsinga. --- Kudzivirira uye Kuderedza Njodzi Nekuti FIP inobva kuFCoV, kudzivirira kunotarisa pakuderedza kuratidzwa uye kushushikana: - kuchengetedza bhokisi remarara rakachena (kucheneswa nguva dzose, huwandu hwakakwana hwemabhokisi), - kudzivirira kuwanda kwemba imwe chete, - kuparadzanisa katsi itsva uye kuongororwa kwekutanga kwehutano, - kuderedza kushushikana (nzvimbo yakagadzikana, kudya kwakanaka), - kudzora zvimwe zvirwere uye majekiseni enguva dzose sezvakakurudzirwa nachiremba wemhuka. --- Mhedziso Zviratidzo zveFIP mumakati zvinogona kuoneka, zvakaita sekukura kwedumbu kana kushaya mweya muFIP yakanyorova, asi zvinogonawo kuva zvishoma, zvakaita sefivha inodzokororwa, kudzikira uremu, kana matambudziko emaziso netsinga muFIP yakaoma. Kuongororwa kunoda kusanganiswa kwekuongororwa kwekiriniki, laboratory, uye mifananidzo, uye kazhinji kunoda kusarudzwa nachiremba wemhuka ane ruzivo. Panyaya yekurapa, kurapwa kwemazuva ano kwehutachiona kwakachinja maonero evaridzi vekatsi vazhinji, asi kubudirira kwakanyanya kana kurapwa kukatanga nekukurumidza uye kuchiongororwa zvakanyanya. Kana katsi yako iine zviratidzo zvinoratidza FIP, unofanirwa kubvunza chiremba wemhuka yako nekukasika kuti uongororwe zvakakwana uye chirongwa chekurapa chakachengeteka uye chakakodzera. Kana uchida, ndinogona kugadzirisa chinyorwa ichi kuti chienderane neshanduro yesainzi (ine mareferensi uye chimiro chejenari) kana shanduro yakakurumbira yemablog evaridzi vezvipfuyo, pamwe nekuwedzera chikamu che "mibvunzo nemhinduro" uye cheki yezviratidzo kune vaverengi.
