Basa reLuteinizing Hormone mukubereka
Homoni yeLuteinizing, inowanzo pfupikiswa seLH, ihomoni inoita basa rakakosha muhurongwa hwekubereka hwemunhu, muvarume nevakadzi. Homoni iyi inogadzirwa negland repituitary, riri pasi pehuropi, uye ine mabasa akasiyana zvichienderana nekuti munhurume here kana kuti munhukadzi. Chinyorwa chino chichanyatsoongorora mashandiro ekubereka ehomoni yeluteinizing, kusanganisira mashandiro ayo, mabasa ayo muhurongwa hwekubereka hwevarume nevakadzi, uye hukama hwayo nehutano nekubereka.
Maitiro uye Kugadzirwa kweLuteinizing Hormone
Chaizvoizvo, kugadzirwa kweLH kunodzorwa nemaitiro ekupindura kwemahormone anosanganisira pituitary gland nehypothalamus. Hypothalamus inoburitsa gonadotropin-releasing hormone (GnRH), iyo inozokurudzira pituitary gland kuti igadzire nekuburitsa LH ne follicle-stimulating hormone (FSH). Maitiro aya anoramba achidzorwa nemazinga eropa emahormone epabonde akadai seestrogen ne testosterone.
Kuvakadzi, kuenderera kwemwedzi kunoita kuti pave nemaitiro ekutenderera kwekugadzirwa kweLH. Mazinga eLH anowedzera zvakanyanya ovulation isati yatanga, zvichikwira zvakanyanya mu "LH surge." Kuvarume, mazinga eLH akasimba uye anogara aripo, zvichinyanya kukurudzira kugadzirwa kwetestosterone.
Basa reLuteinizing Hormone muKubereka Kwevakadzi
Kuenda Kumwedzi uye Kubuda Kwemazamu
Rimwe remabasa makuru eLH kuvakadzi ibasa rayo mumwedzi. Kuenda kumwedzi kunowanzo kamurwa kuita zvikamu zvitatu zvikuru: chikamu che follicular, ovulation, uye chikamu che luteal.
1. Chikamu cheFollicular: Pakutanga kwemwedzi, huwandu hweLH hunenge hwakaderera. FSH inokurudzira kukura nekuibva kwema follicles mumaovari, ane mazai. Ma follicles aya ari kukura anoburitsa estrogen, iyo pakutanga inoderedza kugadzirwa kweLH kuburikidza nemhinduro dzisina kunaka.
2. Kubuda kwechibereko: Kana follicle yasvika pakukura, panobva pawedzera kugadzirwa kweestrogen zvakanyanya. Kuwanda kweestrogen uku kunochinja feedback loop kuita positive, izvo zvinozokurudzira pituitary gland kuburitsa LH (LH surge). Kubuda kwechibereko uku kunoita kuti follicle yakakura iburitse zai rayo nenzira inozivikanwa se ovulation.
3. Luteal Phase: Mushure mekubuda kwembeu, zvasara zve follicle yakaputika zvinova corpus luteum, iyo inoburitsa progesterone uye estrogen shoma. LH inotsigira basa rakakosha re corpus luteum mukugadzirira uterine lining (endometrium) kuti ikwanise kuiswa muchibereko. Kana pamuviri ukasaitika, corpus luteum inoderera, zvichiita kuti mazinga e progesterone ne estrogen adzike, izvo zvinozotungamira kumwedzi.
Kubereka uye Kubata Pamuviri
LH ine basa guru mukubereka kwevakadzi. Pasina kuwedzera kweLH, kubuda kwembeu hakuzoitiki, zvichideredza mikana yekubata pamuviri. Uyezve, LH inotsigira corpus luteum, iyo inokosha pakuchengetedza pamuviri nekukurumidza kusvika placenta yatora basa rekugadzira hormone yeprogesterone inodiwa kuti irambe iripo.
Basa reLuteinizing Hormone muKubereka Kwevarume
Muvarume, luteinizing hormone inoita basa rakasiyana zvishoma asi rakakosha zvakaenzana. Munhengo dzekubereka dzevarume, LH inozivikanwa zvikuru nebasa rayo mukudzora kugadzirwa kwe testosterone kuburikidza nemasero eLeydig mumatestes.
Kugadzirwa kweTestosterone
LH inokurudzira masero eLeydig mumatestes kuti agadzire nekuburitsa testosterone, iyo homoni huru yechirume inokonzeresa kukura kwehunhu hwepabonde hwekutanga nehwechipiri. Testosterone inokosha pakugadzirwa kwespermatogenesis, kugadzirwa kwembeu mumatestes.
Kuumbwa kwembeu
Testosterone, inogadzirwa nemasero eLeydig pasi pesimba reLH, inotsigira kugadzirwa kwembeu mumatubhuru e seminiferous. Testosterone inoshanda pamwe chete neFSH kukurudzira kugadzirwa kwembeu. Pasina LH, kugadzirwa kwembeu ye testosterone kunoderera, zvichikanganisa zvakananga kugadzirwa kwembeu ye spermatozoa uye zvinoderedza huwandu hwembeu ye spermatozoa uye kunaka kwayo.
Basa muKuyaruka
Munguva yekuyaruka, kuwedzera kweLH kunotungamira mukuwedzera kugadzirwa kwe testosterone, izvo zvinokonzeresa kukura kwehunhu hwechirume hwakadai sekukura kwebvudzi remuviri, kudzika kwezwi, uye kuwedzera kwetsandanyama. Nokudaro, LH inoita basa rakakosha mukuchinja kubva paudiki kuenda pakuva munhu mukuru.
Hukama huripo pakati peLH nemamiriro ehutano uye kubereka
Kusaziva zera remunhu
Kushaya homoni mumuviri (hypogonadism) chirwere chinokonzerwa nekushaya homoni mumuviri (sex hormones) yakakwana. Muvarume, izvi zvinogona kuitika nekuda kwekusagadzirwa zvakanaka kweLH, izvo zvinokonzeresa kuderera kwemazinga e testosterone uye kukanganisa kugadzirwa kwespermatozoa.
Polycystic Ovary Syndrome (PCOS)
Muvakadzi, kusaenzana kwemazinga eLH kunogona kuva chiratidzo che polycystic ovary syndrome (PCOS), chirwere chinokanganisa kuenzana kwemahormone ekubereka uye chinogona kukonzera anovulation (kusavapo kweovulation), kusabereka, uye kusaenda kumwedzi.
Kusabereka
Muvanhurume nevanhukadzi, matambudziko ekugadzirwa kana kushanda kweLH anogona kukonzera kusabereka. Kuwanda kweLH kwakanyanya kana kuderera kunogona kuratidza kusagadzikana kwemahormone kunokanganisa kugona kubereka. Saka, kuongororwa kweLH kunowanzoitwa sechikamu chekuongorora kusabereka.
Kurapa Mahormone
Mune zvimwe zviitiko, kurapwa nemahormone kunogona kupihwa kugadzirisa matambudziko ekubereka ane chekuita nemazinga eLH. Semuenzaniso, majekiseni eHCG (human chorionic gonadotropin), ayo anotevedzera LH, anogona kushandiswa kukurudzira ovulation muvakadzi kana kuwedzera kugadzirwa kwetestosterone muvarume.
Mhedziso
Homoni yeLuteinizing (LH) inoita basa rakakosha mukubereka kwevakadzi nevarume. Muvakadzi, LH ndiyo inokonzera ovulation uye inotsigira mashandiro ecorpus luteum panguva yekuenda kumwedzi uye pamuviri. Muvarume, LH inokurudzira kugadzirwa kwetestosterone nemasero eLeydig, ayo anodiwa pakugadzirwa kwembeu uye kukura kwepabonde. Kusawirirana mukugadzirwa kana kushanda kweLH kunogona kutungamira kumatambudziko akasiyana-siyana ehutano nematambudziko ekubereka. Nokudaro, kunzwisisa kwakakwana kwebasa rehomoni iyi kwakakosha pakuongorora nekurapa matambudziko ekubereka.
Kuchengetedza huwandu hwemahormone eLH mumuviri ndicho chinhu chakakosha pahutano hwakanaka hwekubereka.
