Te Mahi a te Myoglobin i roto i te Rokiroki Hāora Uaua
He pūmua nui te myoglobin i roto i te tinana o te tangata me te kararehe, e pā ana ki te kaha o ngā uaua ki te mahi pai. E mōhiotia ana tēnei pūmua ko te "pūngao hāora" i roto i te kiko uaua. Ka nui haere tōna mahi ina hiahiatia he nui te pūngao e ngā uaua, pērā i te wā e whakakorikori tinana ana, e oma ana, e kaukau ana, e mahi tinana ana rānei. Hei mārama ki te hiranga o te myoglobin, me mārama tātou he aha te mea nei, tōna hanganga, me pēhea te penapena hāora, me tōna hononga ki te mahi uaua me ētahi āhuatanga hauora.
He aha te mioglobin?
Ko te mioglobin he pūmua porowhita e kitea ana i roto i ngā pūtau uaua, inā koa ko te uaua angaanga me te uaua ngākau. Ko te mioglobin te mea nui ki te tae whero o te mīti me te uaua, ka puta ai he whero ake te mīti he nui te mioglobin (pērā i te mīti kau) i te mīti he iti ake te mioglobin.
Ko te mahi matua a te myoglobin he here i te hāora me te penapena i roto i ngā pūtau uaua. Ka taea te tuku i tēnei hāora ina hiahia ngā uaua ki te pūngao, ā, kāore e ranea te toto hei whakatutuki i ngā hiahia o nāianei.
Te hanganga o te myoglobin me tōna hononga ki te mahi
He mekameka polypeptide kotahi te mea hanga o te myoglobin (he rerekē i te hemoglobin, e whā ngā waeine). Mā tōna hanganga toru-ahu ka taea e te myoglobin te hanga i tētahi "pōkete" motuhake ka taea te here i ngā ngota hāora. Ko te mea nui o tēnei kaha ko te noho mai o tētahi rōpū heme—he hanganga kei roto te rino (Fe) i waenganui. Ka herea tika tēnei rino ki te hāora.
Nā te mea kotahi anake te waeine o roto, he rerekē ngā āhuatanga here hāora o te myoglobin i te hemoglobin. He nui ake te kaha o te myoglobin ki te hāora i te hemoglobin. He tika tēnei: ka haria e te hemoglobin te hāora mā roto i te toto, ā, me tuku wawe atu ki ngā kiko, engari ko te mahi a te myoglobin he "pupuri" i te hāora hei rahui i roto i ngā uaua, ā, ka tukuna noa iho ina tino tika.
Te tikanga rokiroki hāora i roto i ngā uaua
Ka uru te hāora e manawahia ana e tātou ki roto i ngā pukahukahu, ka herea ki te hemoglobin i roto i ngā toto toto whero, ā, ka haria puta noa i te tinana mā roto i ngā uaua toto. Ina tae te toto ki te kiko uaua, ka tukuna te hāora, ka horapa ki roto i ngā pūtau uaua. Koinei te wāhi e whai wāhi nui ai te myoglobin: ka herea, ka rongoa hoki i te hāora.
He maha ngā painga matua o tēnei rokiroki hāora:
1. Ngā rahui hāora ina piki ohorere te hiahia
Ina kaha ake te mahi a ngā uaua, ka tere te piki o te hiahia mō te hāora hei whakaputa pūngao. Ka whakaratohia e te myoglobin he rahui hāora inamata i mua i te whakatikatika a ngā pūnaha manawa me te pūnaha tohanga toto me te whakanui ake i te tuku hāora mai i ngā pukahukahu.
2. Ka āwhina i te horapa o te hāora ki roto i ngā pūtau uaua
Ka āwhina te myoglobin ki te "tuku" i te hāora mai i te mata o te pūtau ki te mitochondria, ki reira ka puta te pūngao mā te manawa ā-aerobic. Ara, ka āwhina te myoglobin i te tohatoha o te hāora ki roto i ngā pūtau uaua.
3. Āwhina ki te pupuri i te pākia o te tinana
He pai ake te whakaputa pūngao mā te ara aerobic i te ara anaerobic. Mā te noho mai o te myoglobin ka taea e ngā uaua te noho i roto i ngā āhuatanga aerobic mō te wā roa i mua i te huri ki ngā tukanga anaerobic e whakaputa ana i te waikawa lactic.
Te tūranga o te myoglobin i roto i ngā mahi ā-tinana me ngā hākinakina
Ina mahi whakakori tinana tātou, he nui te pūngao e hiahiatia ana e ō tātou tinana. Ko te nuinga o tēnei pūngao ka puta i roto i te mitochondria mā te waikura o ngā matūkai (te hukahuka me te ngako) me te āwhina o te hāora. He mahi nui tā te myoglobin ki te whakarite kia mau tonu te tuku hāora.
I te wāhanga tuatahi o te korikori tinana, ka tukuna teretia e te myoglobin te hāora hei whakatutuki i te hiahia o te uaua. Ka āwhina tēnei ki te whakaiti i te "nama hāora" tuatahi. Ko te nui ake o te myoglobin i roto i te uaua, ko te pai ake o tōna kaha ki te penapena hāora me te mahi mō ngā wā roa me te kore e ngenge.
Mā tēnei anō hoki ka mārama he aha ngā urutaunga ā-tinana o ngā kaitākaro manawanui, pērā i ngā kaioma tawhiti, i ngā kauhoe rānei, i roto i te ahua o te pikinga o te kaha waikura o ngā uaua, tae atu ki te pikinga o te maha o ngā mitochondria me ngā pūmua nui pērā i te myoglobin mā te whakangungu auau.
Te myoglobin i roto i ngā kararehe ruku me ngā urutaunga tino nui
Ko tētahi o ngā tauira tino whakamīharo o te mahi a te myoglobin ka kitea i roto i ngā kararehe ruku pērā i te tohorā, te kekeno, me te aihe. Ka taea e ēnei kararehe te ruku mō ngā wā roa me te kore e manawa. Ko tētahi o ā rātou mea ngaro kei roto i te kukū tino tiketike o te myoglobin i roto i ō rātou uaua. Mā tēnei nui o te myoglobin ka taea e ō rātou uaua te penapena i ngā rahui hāora nui, ka taea ai e rātou te pupuri i te nekehanga me te ora i raro i te wai me te kore he hāora mai i te rangi.
Ina hoki, i roto i ētahi momo, he tino teitei ngā taumata o te myoglobin, ā, he tino mangu te āhua o ngā uaua. Haunga tōna nui, he āhuatanga motuhake anō hoki tō te myoglobin i roto i ngā kararehe ruku e whakaiti ana i te auau o ēnei pūmua ki te piri ki ngā kukū tiketike, e āhei ai rātou ki te noho pumau me te mahi pai.
Te rerekētanga i waenga i te myoglobin me te hemoglobin
Ahakoa e herea ana te hāora e ngā mea e rua, ā, kei roto hoki te heme i roto i ngā mea e rua, he rerekē ngā mahi a te myoglobin me te hemoglobin:
– Te toto toto whero: kei roto i ngā toto toto whero, ko tāna mahi he kawe i te hāora mai i ngā pūkahukahu ki ngā kiko me te whakahoki i te hauhā waro ki ngā pūkahukahu. E whā ōna waeine kia taea ai e ia te here i ngā ngota hāora e whā.
– Myoglobin: kei roto i ngā pūtau uaua, e mahi ana ki te penapena hāora me te āwhina i tōna horapa ki roto i ngā mitochondria. Kotahi anake te waeine iti o tēnei matū, ā, kotahi te ngota hāora e herea ana.
Hei tāpiri atu, he āhuatanga here tahi tō te hemoglobin, arā, mā te here o tētahi hāora ka āwhina i te here o tētahi atu. Kāore he āhuatanga mahi tahi o te myoglobin; ka kaha ake te here o te hāora, e rite ana ki tana mahi hei wāhi rokiroki.
Ngā āhuatanga hauora o te myoglobin
He mea nui anō hoki te myoglobin i roto i ngā horopaki hauora. Ina tino pakaru ngā uaua, hei tauira nā te whara kino, te aituā, ngā āhuatanga rānei pēnei i te rhabdomyolysis, ka turuturu te myoglobin mai i ngā pūtau uaua ki roto i te toto. Ka taea e ngā taumata tiketike o te myoglobin i roto i te toto te uru ki ngā whatukuhu, ā, ka raru pea te whatukuhu.
I roto i ngā mahi haumanu, ko te aroaro o te myoglobin (me ōna hua rānei) i roto i te mimi ka meinga kia pōuri, kia rite ki te tī, ki te kora rānei. He tohu whakatūpato tēnei mō te kino nui o te uaua. Hei tāpiri, i roto i ngā take o te mate ngakau, ka taea hoki te piki ake o te myoglobin nā te kino o te uaua ngakau, ahakoa he nui ake te whakamahi i ngā tohu ngakau motuhake ake (pērā i te troponin).
Whakamutunga
Ko te miokoropini he pūmua uaua e whai wāhi nui ana ki te penapena me te whakarato hāora ki ngā pūtau uaua. Nā tōna kaha ki te hāora, ka taea e te miokoropini te here i te hāora i tukuna mai i te hemoporopini hei rahui. He whai hua tēnei rahui ina hiahia ohorere ngā uaua ki te pūngao, ina kore rānei e taurite te tuku hāora mai i te toto ki ngā hiahia o te mahi. Haunga tana mahi penapena, ka āwhina hoki te miokoropini ki te whakahaere i te horapa o te hāora ki roto i ngā mitochondria, kia pai ake ai te haere o te pākia o te tinana.
E kitea ana te mahi a te myoglobin i roto i ngā hākinakina, te urutau o ngā kararehe ruku, me te rongoā hei tohu mō te pakaru o ngā uaua. Mā te mārama ki te mahi a te myoglobin, ka taea e tātou te mārama ake ki te whakahaere tika a te tinana i te tuku hāora hei tautoko i te nekehanga, te manawanui, me te hauora whānui o ngā uaua.
